Causal relationship between asthma and ulcerative colitis and the mediating role of interleukin-18: a bidirectional Mendelian study and mediation analysis

Causal relationship between asthma and ulcerative colitis and the mediating role of interleukin-18: a bidirectional Mendelian study and mediation analysis

ObjectiveNumerous observational investigations have documented a correlation between asthma and ulcerative colitis(UC). In this Mendelian Randomization (MR) study, we utilized extensive summary data from Genome-Wide Association Studies (GWAS) to further estimate the association between adult-onset a...

Full description

Bibliographic Details
Main Authors: Xin Zou, Rui-Ling Lu, Bin Liao, Shi-Jie Liu, Shi-Xue Dai
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Immunology
Subjects:
asthma
ulcerative colitis
interleukin-18
mediation
Mendelian randomization
tool variables
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1293511/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1293511/full

Similar Items