Involvement of Substance P (SP) and Its Related NK1 Receptor in Primary Sjögren’s Syndrome (pSS) Pathogenesis

Involvement of Substance P (SP) and Its Related NK1 Receptor in Primary Sjögren’s Syndrome (pSS) Pathogenesis

Primary Sjögren’s Syndrome (pSS) is a systemic autoimmune disease that primarily attacks the lacrimal and salivary glands, resulting in impaired secretory function characterized by xerostomia and xerophthalmia. Patients with pSS have been shown to have impaired salivary gland innervation and altered...

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Bibliographic Details
Main Authors: Pamela Rosso, Elena Fico, Serena Colafrancesco, Mario Giuseppe Bellizzi, Roberta Priori, Bruna Cerbelli, Martina Leopizzi, Carla Giordano, Antonio Greco, Paola Tirassa, Cinzia Severini, Massimo Fusconi
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Cells
Subjects:
substance P (SP)
neurokinin receptor 1 (NK1R)
minor salivary gland (MSG)
primary Sjögren’s syndrome (pSS)
sicca syndrome
Online Access:https://www.mdpi.com/2073-4409/12/10/1347

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https://www.mdpi.com/2073-4409/12/10/1347

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