Immunological correlates of protection following vaccination with glucan particles containing Cryptococcus neoformans chitin deacetylases

Immunological correlates of protection following vaccination with glucan particles containing Cryptococcus neoformans chitin deacetylases

Abstract Vaccination with glucan particles (GP) containing the Cryptococcus neoformans chitin deacetylases Cda1 and Cda2 protect mice against experimental cryptococcosis. Here, immunological correlates of vaccine-mediated protection were explored. Studies comparing knockout and wild-type mice demons...

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Bibliographic Details
Main Authors: Ruiying Wang, Lorena V. N. Oliveira, Diana Lourenco, Christina L. Gomez, Chrono K. Lee, Maureen M. Hester, Zhongming Mou, Gary R. Ostroff, Charles A. Specht, Stuart M. Levitz
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-023-00606-0

Internet

https://doi.org/10.1038/s41541-023-00606-0

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