N6 -Methyladenosine Negatively Regulates Human Respiratory Syncytial Virus Replication

N6 -Methyladenosine Negatively Regulates Human Respiratory Syncytial Virus Replication

N6-methyladenosine (m6A) is the most abundant internal modification described in eukaryotic mRNA and several viral RNA including human respiratory syncytial virus (HRSV). Here, we evaluated the impact of m6A writers, erasers and readers on HRSV genomic RNA accumulation and inclusion bodies assembly...

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Bibliographic Details
Main Authors: Fabian Figueroa, Alonso Vega-Gibson, Joseline Catrileo, Aracelly Gaete-Argel, Sebastian Riquelme-Barrios, Luis Antonio Alonso-Palomares, Lorena I. Tapia, Fernando Valiente-Echeverría, Ricardo Soto-Rifo, Monica L. Acevedo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
human respiratory syncytial virus
N6-methyladenosine
RNA modification
inclusion bodies
gRNA synthesis
viral replication
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.739445/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.739445/full

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