The anticonvulsant phytocannabinoids CBGVA and CBDVA inhibit recombinant T-type channels

Introduction: Cannabidiol (CBD) has been clinically approved for intractable epilepsies, offering hope that novel anticonvulsants in the phytocannabinoid class might be developed. Looking beyond CBD, we have recently reported that a series of biosynthetic precursor molecules found in cannabis displa...

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Bibliographic Details
Main Authors: Michael Udoh, Chris Bladen, Marika Heblinski, Jia Lin Luo, Vaishali S. Janve, Lyndsey L. Anderson, Iain S. McGregor, Jonathon C. Arnold
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1048259/full