Renal Failure in Multiple Myeloma "The Myeloma Kidney":State of the Art

Renal failure is present in about 20% of patients with multiple myeloma (MM) at diagnosis. Renal function impairment is usually caused by the so-called "myeloma kidney" and is associated with shortened survival in patients treated with conventional therapy. Renal failure is reve...

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Bibliographic Details
Main Authors: Goldschmidt Hartmut, Lannert Heinrich, Bommer Jurgen, Ho Anthony
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2001-01-01
Series:Saudi Journal of Kidney Diseases and Transplantation
Subjects:
Online Access:http://www.sjkdt.org/article.asp?issn=1319-2442;year=2001;volume=12;issue=2;spage=145;epage=150;aulast=Goldschmidt
Description
Summary:Renal failure is present in about 20% of patients with multiple myeloma (MM) at diagnosis. Renal function impairment is usually caused by the so-called "myeloma kidney" and is associated with shortened survival in patients treated with conventional therapy. Renal failure is reversible in up to 50% of patients, particularly when its degree is moderate and it is related to precipitating factors such as hypercalcemia. In our experience, approximately 10% of newly diagnosed patients with MM have renal failure severe enough to require dialysis. Despite its frequency, there are few reports dealing with MM and renal failure.
ISSN:1319-2442