Early Degenerative Changes in a Spontaneous Osteoarthritis Model Assessed by Nanoindentation

Early Degenerative Changes in a Spontaneous Osteoarthritis Model Assessed by Nanoindentation

Understanding early mechanical changes in articular cartilage (AC) and subchondral bone (SB) is crucial for improved treatment of osteoarthritis (OA). The aim of this study was to develop a method for nanoindentation of fresh, unfixed osteochondral tissue to assess the early changes in the mechanica...

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Bibliographic Details
Main Authors: Sarah Davis, Jurgita Zekonyte, Aikaterina Karali, Marta Roldo, Gordon Blunn
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Bioengineering
Subjects:
nanoindentation
osteoarthritis
osteochondral interface
articular cartilage
subchondral bone
mechanical properties
Online Access:https://www.mdpi.com/2306-5354/10/9/995

Internet

https://www.mdpi.com/2306-5354/10/9/995

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