The path of pre-ribosomes through the nuclear pore complex revealed by electron tomography

Large protein complexes and ribonucleoprotein particles (RNPs) such as pre-ribosomes are transported from the nucleus to the cytoplasm through the nuclear pore complex (NPC). Here the authors use ultrafast freezing and electron tomography to catch snapshots of native RNPs crossing the NPC and estima...

Full description

Bibliographic Details
Main Authors: Franck Delavoie, Vanessa Soldan, Dana Rinaldi, Jean-Yves Dauxois, Pierre-Emmanuel Gleizes
Format: Article
Language:English
Published: Nature Portfolio 2019-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-08342-7