Blood–Brain Barrier Repair of Bevacizumab and Corticosteroid as Prediction of Clinical Improvement and Relapse Risk in Radiation-Induced Brain Necrosis: A Retrospective Observational Study

Blood–Brain Barrier Repair of Bevacizumab and Corticosteroid as Prediction of Clinical Improvement and Relapse Risk in Radiation-Induced Brain Necrosis: A Retrospective Observational Study

BackgroundBlood–brain barrier (BBB) disruption after endothelial damage is a crucial part of radiation-induced brain necrosis (RN), but little is known of BBB disruption quantification and its role in the evaluation of therapeutic effect and prognosis for drug treatment. In this retrospective study,...

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Bibliographic Details
Main Authors: Ruiqi Xue, Meiwei Chen, Jinhua Cai, Zhenhong Deng, Dong Pan, Xiaohuan Liu, Yi Li, Xiaoming Rong, Honghong Li, Yongteng Xu, Qingyu Shen, Yamei Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Oncology
Subjects:
blood–brain barrier permeability
bevacizumab
dynamic contrast-enhanced MR imaging
relapse
radiation-induced brain necrosis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.720417/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.720417/full

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