Tumor necrosis factor α-induced protein 1 as a novel tumor suppressor through selective downregulation of CSNK2B blocks nuclear factor-κB activation in hepatocellular carcinoma

Tumor necrosis factor α-induced protein 1 as a novel tumor suppressor through selective downregulation of CSNK2B blocks nuclear factor-κB activation in hepatocellular carcinoma

Background: Tumor necrosis factor α-induced protein 1 (TNFAIP1) is frequently downregulated in cancer cell lines and promotes cancer cell apoptosis. However, its role, clinical significance and molecular mechanisms in hepatocellular carcinoma (HCC) are unknown. Methods: The expression of TNFAIP1 in...

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Main Authors: Ye Xiao, Shulan Huang, Feng Qiu, Xiaofeng Ding, Yi Sun, Chenxi Wei, Xiang Hu, Ke Wei, Shengwen Long, Lina Xie, Yu Xun, Wen Chen, Zhijian Zhang, Ning Liu, Shuanglin Xiang
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419308187

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http://www.sciencedirect.com/science/article/pii/S2352396419308187

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