Memory B-cell like chronic lymphocytic leukaemia is associated with specific methylation profile of WNT5A promoter and undetectable expression of WNT5A gene

Memory B-cell like chronic lymphocytic leukaemia is associated with specific methylation profile of WNT5A promoter and undetectable expression of WNT5A gene

Genome methylation profiles define naïve-like (n-CLL), memory-like (m-CLL), and intermediate (i-CLL) subsets of chronic lymphocytic leukaemia (CLL). The profiles can be easily determined by the analysis of the five-CpG signature. m-CLL, i-CLL, and n-CLL with the good, intermediate, and poor prognose...

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Bibliographic Details
Main Authors: Lucie Poppova, Sarka Pavlova, Beatriz Gonzalez, Jana Kotaskova, Karla Plevova, Gabrijela Dumbovic, Pavlina Janovska, Vojtech Bystry, Anna Panovska, Lucie Bezdekova, Stanislava Maslejova, Yvona Brychtova, Michael Doubek, Marcela Krzyzankova, Marek Borsky, Jiri Mayer, Vitezslav Bryja, Sergio Alonso, Sarka Pospisilova
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Epigenetics
Subjects:
wnt5a
chronic lymphocytic leukaemia
methylation
i-cll
m-cll
Online Access:http://dx.doi.org/10.1080/15592294.2022.2050004

Internet

http://dx.doi.org/10.1080/15592294.2022.2050004

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