Targeting Tumor-Associated Antigen: A Promising CAR-T Therapeutic Strategy for Glioblastoma Treatment

Targeting Tumor-Associated Antigen: A Promising CAR-T Therapeutic Strategy for Glioblastoma Treatment

Chimeric antigen receptor T cells (CAR-T) therapy is a prospective therapeutic strategy for blood cancers tumor, especially leukemia, but it is not effective for solid tumors. Glioblastoma (GBM) is a highly immunosuppressive and deadly malignant tumor with poor responses to immunotherapies. Although...

Full description

Bibliographic Details
Main Authors: Guidong Zhu, Qing Zhang, Junwen Zhang, Fusheng Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Pharmacology
Subjects:
car-t
glioblastoma
tumor-associated antigen
targeted therapy
immunotherapy
tumor microenvironment
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.661606/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.661606/full

Similar Items