Sustained productivity in recombinant Chinese Hamster Ovary (CHO) cell lines: proteome analysis of the molecular basis for a process-related phenotype

<p>Abstract</p> <p>Background</p> <p>The ability of mammalian cell lines to sustain cell specific productivity (Qp) over the full duration of bioprocess culture is a highly desirable phenotype, but the molecular basis for sustainable productivity has not been previously...

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Bibliographic Details
Main Authors: Gammell Patrick, Clarke Colin, O'Sullivan Finbar, Keenan Joanne, Barron Niall, Henry Michael, Doolan Padraig, Meleady Paula, Melville Mark W, Leonard Mark, Clynes Martin
Format: Article
Language:English
Published: BMC 2011-07-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/11/78