BNIP‐2 Activation of Cellular Contractility Inactivates YAP for H9c2 Cardiomyoblast Differentiation

BNIP‐2 Activation of Cellular Contractility Inactivates YAP for H9c2 Cardiomyoblast Differentiation

Abstract Rho GTPases and Hippo kinases are key regulators of cardiomyoblast differentiation. However, how these signaling axes are coordinated spatiotemporally remains unclear. Here, the central and multifaceted roles of the BCH domain containing protein, BNIP‐2, in orchestrating the expression of t...

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Bibliographic Details
Main Authors: Darren Chen Pei Wong, Jingwei Xiao, Ti Weng Chew, Meng Pan, Chang Jie Mick Lee, Jing Wen Ang, Ivan Yow, T. Thivakar, Matthew Ackers‐Johnson, Nicole Jia Wen Lee, Roger Sik‐Yin Foo, Pakorn Kanchanawong, Boon Chuan Low
Format: Article
Language:English
Published: Wiley 2022-11-01
Series:Advanced Science
Subjects:
BNIP‐2
cardiomyoblast
cellular contractility
LATS1
mechanotransduction
RhoA
Online Access:https://doi.org/10.1002/advs.202202834

Internet

https://doi.org/10.1002/advs.202202834

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