Hypoxia‐Inducible Factor‐2α Signaling in the Skeletal System
ABSTRACT Hypoxia‐inducible factors (HIFs) are oxygen‐dependent heterodimeric transcription factors that mediate molecular responses to reductions in cellular oxygen (hypoxia). HIF signaling involves stable HIF‐β subunits and labile, oxygen‐sensitive HIF‐α subunits. Under hypoxic conditions, the HIF‐...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2023-04-01
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Series: | JBMR Plus |
Subjects: | |
Online Access: | https://doi.org/10.1002/jbm4.10733 |