Non‐DNA‐binding cofactors enhance DNA‐binding specificity of a transcriptional regulatory complex

Non‐DNA‐binding cofactors enhance DNA‐binding specificity of a transcriptional regulatory complex

Abstract Recruitment of cofactors to specific DNA sites is integral for specificity in gene regulation. As a model system, we examined how targeting and transcriptional control of the sulfur metabolism genes in Saccharomyces cerevisiae is governed by recruitment of the transcriptional co‐activator M...

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Bibliographic Details
Main Authors: Trevor Siggers, Michael H Duyzend, Jessica Reddy, Sidra Khan, Martha L Bulyk
Format: Article
Language:English
Published: Springer Nature 2011-12-01
Series:Molecular Systems Biology
Subjects:
cofactor
DNA‐binding affinities
DNA binding site
sulfur metabolism
transcription factor
Online Access:https://doi.org/10.1038/msb.2011.89

Internet

https://doi.org/10.1038/msb.2011.89

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