Application of metagenomic next-generation sequencing for rapid molecular identification in spinal infection diagnosis

Application of metagenomic next-generation sequencing for rapid molecular identification in spinal infection diagnosis

ObjectiveThis study aimed to determine the sensitivity and specificity of metagenomic next−generation sequencing (mNGS) for detecting pathogens in spinal infections and to identify the differences in the diagnostic performance between mNGS and targeted next−generation sequencing (tNGS).MethodsA tota...

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Bibliographic Details
Main Authors: Hui Lv, Sheng Liao, Zhenzhen Shi, Yuan Guo, JianHong Zhou, Hui Chen, Fei Luo, JianZhong Xu, ZhongRong Zhang, ZeHua Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
spinal infection
metagenomic next-generation sequencing
targeted next-generation sequencing
spinal tuberculosis
sensitivity
diagnosis
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2024.1382635/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2024.1382635/full

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