Long-term administration of morphine specifically alters the level of protein expression in different brain regions and affects the redox state

We investigated the changes in redox state and protein expression in selected parts of the rat brain induced by a 4 week administration of morphine (10 mg/kg/day). We found a significant reduction in lipid peroxidation that mostly persisted for 1 week after morphine withdrawal. Morphine treatment le...

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Bibliographic Details
Main Authors: Hejnova Lucie, Hronova Anna, Drastichova Zdenka, Novotny Jiri
Format: Article
Language:English
Published: De Gruyter 2024-04-01
Series:Open Life Sciences
Subjects:
Online Access:https://doi.org/10.1515/biol-2022-0858