Gestational diabetes augments group B Streptococcus infection by disrupting maternal immunity and the vaginal microbiota

Abstract Group B Streptococcus (GBS) is a pervasive perinatal pathogen, yet factors driving GBS dissemination in utero are poorly defined. Gestational diabetes mellitus (GDM), a complication marked by dysregulated immunity and maternal microbial dysbiosis, increases risk for GBS perinatal disease. U...

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Bibliographic Details
Main Authors: Vicki Mercado-Evans, Marlyd E. Mejia, Jacob J. Zulk, Samantha Ottinger, Zainab A. Hameed, Camille Serchejian, Madelynn G. Marunde, Clare M. Robertson, Mallory B. Ballard, Simone H. Ruano, Natalia Korotkova, Anthony R. Flores, Kathleen A. Pennington, Kathryn A. Patras
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-45336-6