A primate specific extra domain in the molecular chaperone Hsp90.

Hsp90 (heat shock protein 90) is an essential molecular chaperone that mediates folding and quality control of client proteins. Many of them such as protein kinases, steroid receptors and transcription factors are involved in cellular signaling processes. Hsp90 undergoes an ATP hydrolysis dependent...

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Bibliographic Details
Main Authors: Vishwadeepak Tripathi, Wolfgang M J Obermann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3739785?pdf=render