Synthesis and Preclinical Evaluation of Small-Molecule Prostate-Specific Membrane Antigen-Targeted Abiraterone Conjugate

Synthesis and Preclinical Evaluation of Small-Molecule Prostate-Specific Membrane Antigen-Targeted Abiraterone Conjugate

Prostate cancer is the second most common type of cancer among men. The main method of its treatment is androgen deprivation therapy, which has a wide range of side effects. One of the solutions to this challenge is the targeted delivery of drugs to prostate cancer cells. In this study, we performed...

Full description

Bibliographic Details
Main Authors: Aleksei E. Machulkin, Ekaterina A. Nimenko, Nikolay U. Zyk, Anastasiia A. Uspenskaia, Galina B. Smirnova, Irina I. Khan, Vadim S. Pokrovsky, Alexander N. Vaneev, Roman V. Timoshenko, Vugara V. Mamed-Nabizade, Maria V. Zavertkina, Alexander Erofeev, Petr Gorelkin, Alexander G. Majouga, Nikolay V. Zyk, Elena S. Khazanova, Elena K. Beloglazkina
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Molecules
Subjects:
prostate cancer
abiraterone
drug delivery
prostate-specific membrane antigen
Online Access:https://www.mdpi.com/1420-3049/27/24/8795

Internet

https://www.mdpi.com/1420-3049/27/24/8795

Similar Items