Catalase application in cancer therapy: Simultaneous focusing on hypoxia attenuation and macrophage reprogramming

Catalase application in cancer therapy: Simultaneous focusing on hypoxia attenuation and macrophage reprogramming

The tumor microenvironment (TME), as an immunosuppressive milieu, has a critical role in tumor progression and increases resistance to the conventional treatments. Among the abundant immunosuppressive cells in the TME, tumor-associated macrophages (TAMs) could be a promising target for reprogramming...

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Bibliographic Details
Main Authors: Alireza Najafi, Maryam Keykhaee, Hossein Khorramdelazad, Mohammad Yahya Karimi, Leila Nejatbakhsh Samimi, Nazanin Aghamohamadi, Milad Karimi, Reza Falak, Mehdi Khoobi
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Catalase
Hypoxia
Macrophage polarization
Nanozyme
Tumor-associated macrophage
Tumor microenvironment
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222008721

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http://www.sciencedirect.com/science/article/pii/S0753332222008721

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