TERT Mutation Is Accompanied by Neutrophil Infiltration and Contributes to Poor Survival in Isocitrate Dehydrogenase Wild-Type Glioma

TERT Mutation Is Accompanied by Neutrophil Infiltration and Contributes to Poor Survival in Isocitrate Dehydrogenase Wild-Type Glioma

Mutation of the telomerase reverse transcriptase (TERT) promoter has been demonstrated as an unfavorable prognostic marker in patients with isocitrate dehydrogenase wild-type (IDHwt) glioma. This study aimed to investigate the immune role of TERT promoter mutation status which could improve prognost...

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Bibliographic Details
Main Authors: Mengqi Gao, Yi Lin, Xing Liu, Zheng Zhao, Zhiyuan Zhu, Hongbo Zhang, Yunchao Ban, Yanan Bie, Xiaozheng He, Xiang Sun, Shizhong Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
TERT mutation
glioma
IDH mutation
neutrophil
chemokines
RNA-seq
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.654407/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.654407/full

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