Immunization of mice with the self-peptide ACBP coupled to keyhole limpet hemocyanin

Summary: Keyhole limpet hemocyanin (KLH) is a glycosylated multi-subunit metalloprotein that elicits a strong nonspecific immune activation, thus inducing both cellular and humoral immune responses. The exceptional immunogenicity of this protein can be leveraged to vaccinate mice against self-antige...

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Bibliographic Details
Main Authors: Léa Montégut, Hui Chen, José Manuel Bravo-San Pedro, Omar Motiño, Isabelle Martins, Guido Kroemer
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166721008017