β2-microglobulin alters the profiles of inflammatory cytokines and of matrix metalloprotease in macrophages derived from the osteoarthritic synovium

Several studies have implicated b2-microglobulin (B2M) in osteoarthritis (OA) pathology. Of the main constituents of synovial tissue, synovial fibroblasts and macrophages, the latter play a pivotal role in inflammation. Although several studies have investigated the effects of B2M on synovial fibrob...

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Bibliographic Details
Main Authors: Kyoko Muneshige, Kentaro Uchida, Jun Aikawa, Dai Iwase, Shotaro Takano, Masayuki Miyagi, Gen Inoue, Masashi Takaso
Format: Article
Language:English
Published: Termedia Publishing House 2023-01-01
Series:Central European Journal of Immunology
Subjects:
Online Access:https://www.termedia.pl/-2-microglobulin-alters-the-profiles-of-inflammatory-cytokines-and-of-matrix-metalloprotease-in-macrophages-derived-from-the-osteoarthritic-synovium,10,49898,1,1.html