Prospects of ultrasonically extracted food bioactives in the field of non-invasive biomedical applications – A review
Foods incorporated with bioactive compounds, called nutraceuticals, can fight or prevent or alleviate diseases. The contribution of nutraceuticals or phytochemicals to non-invasive biomedical applications is increasing. Although there are many traditional methods for extracting bioactive compounds o...
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Format: | Article |
Language: | English |
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Elsevier
2022-09-01
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Series: | Ultrasonics Sonochemistry |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S1350417722002176 |
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author | Addanki Mounika Bhaargavi Ilangovan Sushmita Mandal Waghaye Shraddha Yashwant Swetha Priya Gali Akalya Shanmugam |
author_facet | Addanki Mounika Bhaargavi Ilangovan Sushmita Mandal Waghaye Shraddha Yashwant Swetha Priya Gali Akalya Shanmugam |
author_sort | Addanki Mounika |
collection | DOAJ |
description | Foods incorporated with bioactive compounds, called nutraceuticals, can fight or prevent or alleviate diseases. The contribution of nutraceuticals or phytochemicals to non-invasive biomedical applications is increasing. Although there are many traditional methods for extracting bioactive compounds or secondary metabolites, these processes come with many disadvantages like lower yield, longer process time, high energy consumption, more usage of solvent, yielding low active principles with low efficacy against diseases, poor quality, poor mass transfer, higher extraction temperature, etc. However, nullifying all these disadvantages of a non-thermal technology, ultrasound has played a significant role in delivering them with higher yield and improved bio-efficacy. The physical and chemical effects of acoustic cavitation are the crux of the output. This review paper primarily discusses the ultrasound-assisted extraction (USAE) of bioactives in providing non-invasive prevention and cure to diseases and bodily dysfunctions in human and animal models. The outputs of non-invasive bioactive components in terms of yield and the clinical efficacy in either in vitro or in vitro conditions are discussed in detail. The non-invasive biomedical applications of USAE bioactives providing anticancer, antioxidant, cardiovascular health, antidiabetic, and antimicrobial benefits are analyzed in-depth and appraised. This review additionally highlights the improved performance of USAE compounds against conventionally extracted compounds. In addition, an exhaustive analysis is performed on the role and application of the food bioactives in vivo and in vitro systems, mainly for promoting these efficient USAE bioactives in non-invasive biomedical applications. Also, the review explores the recovery of bioactives from the less explored food sources like cactus pear fruit, ash gourd, sweet granadilla, basil, kokum, baobab, and the food processing industrial wastes like peel, pomace, propolis, wine residues, bran, etc., which is rare in literature. |
first_indexed | 2024-04-12T22:36:58Z |
format | Article |
id | doaj.art-2ae32644c69842d99318176e110f3489 |
institution | Directory Open Access Journal |
issn | 1350-4177 |
language | English |
last_indexed | 2024-04-12T22:36:58Z |
publishDate | 2022-09-01 |
publisher | Elsevier |
record_format | Article |
series | Ultrasonics Sonochemistry |
spelling | doaj.art-2ae32644c69842d99318176e110f34892022-12-22T03:13:50ZengElsevierUltrasonics Sonochemistry1350-41772022-09-0189106121Prospects of ultrasonically extracted food bioactives in the field of non-invasive biomedical applications – A reviewAddanki Mounika0Bhaargavi Ilangovan1Sushmita Mandal2Waghaye Shraddha Yashwant3Swetha Priya Gali4Akalya Shanmugam5Food Processing Business Incubation Centre, National Institute of Food Technology, Entrepreneurship and Management - Thanjavur, IndiaFood Processing Business Incubation Centre, National Institute of Food Technology, Entrepreneurship and Management - Thanjavur, IndiaFood Processing Business Incubation Centre, National Institute of Food Technology, Entrepreneurship and Management - Thanjavur, IndiaFood Processing Business Incubation Centre, National Institute of Food Technology, Entrepreneurship and Management - Thanjavur, IndiaFood Processing Business Incubation Centre, National Institute of Food Technology, Entrepreneurship and Management - Thanjavur, IndiaFood Processing Business Incubation Centre, National Institute of Food Technology, Entrepreneurship and Management - Thanjavur, India; Centre of Excellence in Non-Thermal Processing, National Institute of Food Technology, Entrepreneurship and Management - Thanjavur, India; Corresponding author at: Food Processing Business Incubation Centre, National Institute of Food Technology, Entrepreneurship and Management - Thanjavur, India.Foods incorporated with bioactive compounds, called nutraceuticals, can fight or prevent or alleviate diseases. The contribution of nutraceuticals or phytochemicals to non-invasive biomedical applications is increasing. Although there are many traditional methods for extracting bioactive compounds or secondary metabolites, these processes come with many disadvantages like lower yield, longer process time, high energy consumption, more usage of solvent, yielding low active principles with low efficacy against diseases, poor quality, poor mass transfer, higher extraction temperature, etc. However, nullifying all these disadvantages of a non-thermal technology, ultrasound has played a significant role in delivering them with higher yield and improved bio-efficacy. The physical and chemical effects of acoustic cavitation are the crux of the output. This review paper primarily discusses the ultrasound-assisted extraction (USAE) of bioactives in providing non-invasive prevention and cure to diseases and bodily dysfunctions in human and animal models. The outputs of non-invasive bioactive components in terms of yield and the clinical efficacy in either in vitro or in vitro conditions are discussed in detail. The non-invasive biomedical applications of USAE bioactives providing anticancer, antioxidant, cardiovascular health, antidiabetic, and antimicrobial benefits are analyzed in-depth and appraised. This review additionally highlights the improved performance of USAE compounds against conventionally extracted compounds. In addition, an exhaustive analysis is performed on the role and application of the food bioactives in vivo and in vitro systems, mainly for promoting these efficient USAE bioactives in non-invasive biomedical applications. Also, the review explores the recovery of bioactives from the less explored food sources like cactus pear fruit, ash gourd, sweet granadilla, basil, kokum, baobab, and the food processing industrial wastes like peel, pomace, propolis, wine residues, bran, etc., which is rare in literature.http://www.sciencedirect.com/science/article/pii/S1350417722002176Non-invasiveBiomedical applicationUltrasound-assisted extractionBioactivesIn vivoEfficacy |
spellingShingle | Addanki Mounika Bhaargavi Ilangovan Sushmita Mandal Waghaye Shraddha Yashwant Swetha Priya Gali Akalya Shanmugam Prospects of ultrasonically extracted food bioactives in the field of non-invasive biomedical applications – A review Ultrasonics Sonochemistry Non-invasive Biomedical application Ultrasound-assisted extraction Bioactives In vivo Efficacy |
title | Prospects of ultrasonically extracted food bioactives in the field of non-invasive biomedical applications – A review |
title_full | Prospects of ultrasonically extracted food bioactives in the field of non-invasive biomedical applications – A review |
title_fullStr | Prospects of ultrasonically extracted food bioactives in the field of non-invasive biomedical applications – A review |
title_full_unstemmed | Prospects of ultrasonically extracted food bioactives in the field of non-invasive biomedical applications – A review |
title_short | Prospects of ultrasonically extracted food bioactives in the field of non-invasive biomedical applications – A review |
title_sort | prospects of ultrasonically extracted food bioactives in the field of non invasive biomedical applications a review |
topic | Non-invasive Biomedical application Ultrasound-assisted extraction Bioactives In vivo Efficacy |
url | http://www.sciencedirect.com/science/article/pii/S1350417722002176 |
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