FOXO1 regulates pentose phosphate pathway-mediated induction of developmental erythropoiesis

Primitive, neonatal and adult erythroid cells have been previously shown to have an active pentose phosphate pathway (PPP) that fuels various processes. However, it is unclear whether the PPP plays a role during the emergence of erythroid progenitors from hemogenic endothelium (HE). In this study, w...

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Bibliographic Details
Main Authors: Anuntxi Monsalve, Isaac Canals, Leal Oburoglu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.1039636/full