DDX41 Recognizes RNA/DNA Retroviral Reverse Transcripts and Is Critical for <italic toggle="yes">In Vivo</italic> Control of Murine Leukemia Virus Infection

ABSTRACT Host recognition of viral nucleic acids generated during infection leads to the activation of innate immune responses essential for early control of virus. Retrovirus reverse transcription creates numerous potential ligands for cytosolic host sensors that recognize foreign nucleic acids, in...

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Bibliographic Details
Main Authors: Spyridon Stavrou, Alexya N. Aguilera, Kristin Blouch, Susan R. Ross
Format: Article
Language:English
Published: American Society for Microbiology 2018-07-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mBio.00923-18