DDX41 Recognizes RNA/DNA Retroviral Reverse Transcripts and Is Critical for <italic toggle="yes">In Vivo</italic> Control of Murine Leukemia Virus Infection
ABSTRACT Host recognition of viral nucleic acids generated during infection leads to the activation of innate immune responses essential for early control of virus. Retrovirus reverse transcription creates numerous potential ligands for cytosolic host sensors that recognize foreign nucleic acids, in...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2018-07-01
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Series: | mBio |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/mBio.00923-18 |