Transcriptomic analysis of monocytes from HIV-positive men on antiretroviral therapy reveals effects of tobacco smoking on interferon and stress response systems associated with depressive symptoms

Abstract Background Tobacco smoking induces immunomodulatory and pro-inflammatory effects associated with transcriptome changes in monocytes and other immune cell types. While smoking is prevalent in HIV-infected (HIV+) individuals, few studies have investigated its effects on gene expression in thi...

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Bibliographic Details
Main Authors: David R. Lorenz, Vikas Misra, Dana Gabuzda
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Human Genomics
Subjects:
Online Access:https://doi.org/10.1186/s40246-019-0247-x