CLAMP and Zelda function together to promote Drosophila zygotic genome activation

CLAMP and Zelda function together to promote Drosophila zygotic genome activation

During the essential and conserved process of zygotic genome activation (ZGA), chromatin accessibility must increase to promote transcription. Drosophila is a well-established model for defining mechanisms that drive ZGA. Zelda (ZLD) is a key pioneer transcription factor (TF) that promotes ZGA in th...

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Bibliographic Details
Main Authors: Jingyue Duan, Leila Rieder, Megan M Colonnetta, Annie Huang, Mary Mckenney, Scott Watters, Girish Deshpande, William Jordan, Nicolas Fawzi, Erica Larschan
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-08-01
Series:eLife
Subjects:
zygotic genome activation
CLAMP
Zelda
Drosophila embryo
pioneer TF
Online Access:https://elifesciences.org/articles/69937

Internet

https://elifesciences.org/articles/69937

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