Post-Transcriptional Effects of miRNAs on PCSK7 Expression and Function: miR-125a-5p, miR-143-3p, and miR-409-3p as Negative Regulators

The regulatory mechanism of <i>PCSK7</i> gene is still unknown, although its encoded protein PC7 is the most ancient and highly conserved of all proprotein convertases and exhibits enzymatic and non-enzymatic functions in liver triglyceride regulation. Bioinformatics algorithms were used...

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Bibliographic Details
Main Authors: Mahshid Malakootian, Parisa Naeli, Seyed Javad Mowla, Nabil G. Seidah
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/12/7/588