Microbiological Screening of 5-Functionalized Pyrazoles for the Future Development of Optimized Pyrazole-Based Delivery Systems

Microbiological Screening of 5-Functionalized Pyrazoles for the Future Development of Optimized Pyrazole-Based Delivery Systems

The pyrazole ring represents a widely applied chemical scaffold in medicinal chemistry research and we have observed that the physicochemical and biological features of highly substituted pyrazoles can be successfully improved by their encapsulation in dendrimer nanoparticles (NPs). For the future d...

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Bibliographic Details
Main Authors: Chiara Brullo, Debora Caviglia, Andrea Spallarossa, Silvana Alfei, Scott G. Franzblau, Bruno Tasso, Anna Maria Schito
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Pharmaceutics
Subjects:
pyrazole
5-aminopyrazoles
antibacterial activity
Gram-positive species
<i>Staphylococcus</i> genus
in silico pharmacokinetic properties prediction
Online Access:https://www.mdpi.com/1999-4923/14/9/1770

Internet

https://www.mdpi.com/1999-4923/14/9/1770

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