The Effect of Cigarette Smoke Exposure on the Development of Inflammation in Lungs, Gut and Joints of TNFΔARE Mice.

The inflammatory cytokine TNF-α is a central mediator in many immune-mediated diseases, such as Crohn's disease (CD), spondyloarthritis (SpA) and chronic obstructive pulmonary disease (COPD). Epidemiologic studies have shown that cigarette smoking (CS) is a prominent common risk factor in these...

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Bibliographic Details
Main Authors: Liesbeth Allais, Smitha Kumar, Karlijn Debusschere, Stephanie Verschuere, Tania Maes, Rebecca De Smet, Griet Conickx, Martine De Vos, Debby Laukens, Guy F Joos, Guy G Brusselle, Dirk Elewaut, Claude A Cuvelier, Ken R Bracke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4629889?pdf=render