Comparison of rule- and ordinary differential equation-based dynamic model of DARPP-32 signalling network

Dynamic modelling has considerably improved our understanding of complex molecular mechanisms. Ordinary differential equations (ODEs) are the most detailed and popular approach to modelling the dynamics of molecular systems. However, their application in signalling networks, characterised by multi-s...

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Bibliographic Details
Main Authors: Emilia M. Wysocka, Matthew Page, James Snowden, T. Ian Simpson
Format: Article
Language:English
Published: PeerJ Inc. 2022-12-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/14516.pdf