Lack of ZNF365 Drives Senescence and Exacerbates Experimental Lung Fibrosis

Lack of ZNF365 Drives Senescence and Exacerbates Experimental Lung Fibrosis

Idiopathic pulmonary fibrosis (IPF) is characterized by aberrant activation of the alveolar epithelium, the expansion of the fibroblast population, and the accumulation of extracellular matrix. Global gene expression of human lung fibroblasts stimulated with TGFβ-1, a strong fibrotic mediator reveal...

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Bibliographic Details
Main Authors: Juan Urista, Mariel Maldonado, Fernanda Toscano-Marquez, Remedios Ramírez, Yalbi Itzel Balderas-Martínez, Carina Becerril, Yair Romero, Moisés Selman, Annie Pardo
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cells
Subjects:
zinc finger protein ZNF365
pulmonary fibrosis
TGFβ-1
cellular senescence
Online Access:https://www.mdpi.com/2073-4409/11/18/2848

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https://www.mdpi.com/2073-4409/11/18/2848

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