Transcriptional Profiling of Normal, Stenotic, and Regurgitant Human Aortic Valves

Transcriptional Profiling of Normal, Stenotic, and Regurgitant Human Aortic Valves

The genetic mechanisms underlying aortic stenosis (AS) and aortic insufficiency (AI) disease progression remain unclear. We hypothesized that normal aortic valves and those with AS or AI all exhibit unique transcriptional profiles. Normal control (NC) aortic valves were collected from non-matched do...

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Bibliographic Details
Main Authors: Christina L. Greene, Kevin J. Jaatinen, Hanjay Wang, Tiffany K. Koyano, Mary S. Bilbao, Y. Joseph Woo
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Genes
Subjects:
aortic stenosis
aortic insufficiency
transcriptional profiling
RNA sequencing
Online Access:https://www.mdpi.com/2073-4425/11/7/789

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https://www.mdpi.com/2073-4425/11/7/789

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