Oxidized SOD1 accelerates cellular senescence in neural stem cells
Abstract Background Neural stem cells (NSCs), especially human NSCs, undergo cellular senescence characterized by an irreversible proliferation arrest and loss of stemness after prolonged culture. While compelling correlative data have been generated to support the oxidative stress theory as one of...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-02-01
|
| Series: | Stem Cell Research & Therapy |
| Online Access: | https://doi.org/10.1186/s13287-024-03669-5 |