WZ-3146 acts as a novel small molecule inhibitor of KIF4A to inhibit glioma progression by inducing apoptosis

WZ-3146 acts as a novel small molecule inhibitor of KIF4A to inhibit glioma progression by inducing apoptosis

Abstract Background Glioma is considered the most common primary malignant tumor of the central nervous system. Although traditional treatments have not achieved satisfactory outcomes, recently, targeted therapies for glioma have shown promising efficacy. However, due to the single-target nature of...

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Bibliographic Details
Main Authors: Tao Yan, Qing Jiang, Guangpu Ni, Haofeng Ma, Yun Meng, Guiqiong Kang, Meifang Xu, Fei Peng, Huadong Li, Xin Chen, Mingguang Wang
Format: Article
Language:English
Published: BMC 2024-06-01
Series:Cancer Cell International
Subjects:
Glioma
Targeted therapy
KIF4A
WZ-3146
Online Access:https://doi.org/10.1186/s12935-024-03409-y

Internet

https://doi.org/10.1186/s12935-024-03409-y

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