Tranexamic acid for haemostasis and beyond: does dose matter?

Abstract Tranexamic acid (TXA) is a widely used antifibrinolytic agent that has been used since the 1960’s to reduce blood loss in various conditions. TXA is a lysine analogue that competes for the lysine binding sites in plasminogen and tissue-type plasminogen activator impairing its interaction wi...

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Bibliographic Details
Main Authors: Tammy Lam, Robert L. Medcalf, Geoffrey C. Cloud, Paul S. Myles, Charithani B. Keragala
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Thrombosis Journal
Subjects:
Online Access:https://doi.org/10.1186/s12959-023-00540-0