Discovery and Differential Processing of HLA Class II-Restricted Minor Histocompatibility Antigen LB-PIP4K2A-1S and Its Allelic Variant by Asparagine Endopeptidase

Discovery and Differential Processing of HLA Class II-Restricted Minor Histocompatibility Antigen LB-PIP4K2A-1S and Its Allelic Variant by Asparagine Endopeptidase

Minor histocompatibility antigens are the main targets of donor-derived T-cells after allogeneic stem cell transplantation. Identification of these antigens and understanding their biology are a key requisite for more insight into how graft vs. leukemia effect and graft vs. host disease could be sep...

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Bibliographic Details
Main Authors: Anita N. Kremer, Judith Bausenwein, Ellie Lurvink, Andreas E. Kremer, Caroline E. Rutten, Cornelis A. M. van Bergen, Sascha Kretschmann, Edith van der Meijden, Maria W. Honders, Daniela Mazzeo, Colin Watts, Andreas Mackensen, J. H. Frederik Falkenburg, Marieke Griffioen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Immunology
Subjects:
minor histocompatibility antigens
CD4 T-cells
HLA class II
allogeneic stem cell transplantation
graft vs. leukemia effect
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00381/full

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https://www.frontiersin.org/article/10.3389/fimmu.2020.00381/full

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