The PINK1/Parkin signaling pathway-mediated mitophagy: a forgotten protagonist in myocardial ischemia/reperfusion injury

The PINK1/Parkin signaling pathway-mediated mitophagy: a forgotten protagonist in myocardial ischemia/reperfusion injury

Myocardial ischemia causes extensive damage, further exacerbated by reperfusion, a phenomenon called myocardial ischemia/reperfusion injury (MIRI). Nowadays, the pathological mechanisms of MIRI have received extensive attention. Oxidative stress, multiple programmed cell deaths, inflammation and oth...

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Bibliographic Details
Main Authors: Xiaopeng Zhao, Zheng Wang, Lijie Wang, Tao Jiang, Dan Dong, Mingli Sun
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Pharmacological Research
Subjects:
Mitophagy
The PINK1/Parkin signaling pathway
MIRI
Pathological mechanisms
Potential interventions
Intervention protocols
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661824004110

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http://www.sciencedirect.com/science/article/pii/S1043661824004110

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