Biomaterial-based endochondral bone regeneration: a shift from traditional tissue engineering paradigms to developmentally inspired strategies

There is an urgent, clinical need for an alternative to the use of autologous grafts for the ever increasing number of bone grafting procedures performed annually. Herein, we describe a developmentally inspired approach to bone tissue engineering, which focuses on leveraging biomaterials as platform...

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Bibliographic Details
Main Authors: E.J. Sheehy, D.J. Kelly, F.J. O'Brien
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Materials Today Bio
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006419300225