Interaction between therapeutic interventions for Alzheimer’s disease and physiological Aβ clearance mechanisms

Most therapeutic agents are designed to target a molecule or pathway without consideration of the mechanisms involved in the physiological turnover or removal of that target. In light of this and in particular for Alzheimer’s disease, a number of therapeutic interventions are presently being develo...

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Bibliographic Details
Main Authors: Christopher eMorrone, Mingzhe eLiu, Sandra E Black, Joanne eMclaurin
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2015.00064/full