Differential regulation of Aβ42-induced neuronal C1q synthesis and microglial activation

<p>Abstract</p> <p>Expression of C1q, an early component of the classical complement pathway, has been shown to be induced in neurons in hippocampal slices, following accumulation of exogenous Aβ42. Microglial activation was also detected by surface marker expression and cytokine p...

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Bibliographic Details
Main Authors: Tenner Andrea J, Fan Rong
Format: Article
Language:English
Published: BMC 2005-01-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/2/1/1