Galectin-3 Negatively Regulates Hippocampus-Dependent Memory Formation through Inhibition of Integrin Signaling and Galectin-3 Phosphorylation

Galectin-3 Negatively Regulates Hippocampus-Dependent Memory Formation through Inhibition of Integrin Signaling and Galectin-3 Phosphorylation

Galectin-3, a member of the galectin protein family, has been found to regulate cell proliferation, inhibit apoptosis and promote inflammatory responses. Galectin-3 is also expressed in the adult rat hippocampus, but its role in learning and memory function is not known. Here, we found that contextu...

Full description

Bibliographic Details
Main Authors: Yan-Chu Chen, Yun-Li Ma, Cheng-Hsiung Lin, Sin-Jhong Cheng, Wei-Lun Hsu, Eminy H.-Y. Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Molecular Neuroscience
Subjects:
galectin-3
integrin signaling
phosphorylation
contextual fear conditioning learning
spatial learning
hippocampus
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2017.00217/full

Internet

http://journal.frontiersin.org/article/10.3389/fnmol.2017.00217/full

Similar Items