Propofol anesthesia improves stroke outcomes over isoflurane anesthesia—a longitudinal multiparametric MRI study in a rodent model of transient middle cerebral artery occlusion

Propofol anesthesia improves stroke outcomes over isoflurane anesthesia—a longitudinal multiparametric MRI study in a rodent model of transient middle cerebral artery occlusion

General anesthesia is routinely used in endovascular thrombectomy procedures, for which volatile gas and/or intravenous propofol are recommended. Emerging evidence suggests propofol may have superior effects on disability and/or mortality rates, but a mode-of-action underlying these class-specific e...

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Bibliographic Details
Main Authors: Bart A. A. Franx, Geralda A. F. van Tilborg, Annette van der Toorn, Caroline L. van Heijningen, Diederik W. J. Dippel, Irene C. van der Schaaf, Rick M. Dijkhuizen, on behalf of the CONTRAST consortium
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Neurology
Subjects:
experimental stroke
acute ischemic stroke
reperfusion
general anesthesia
isoflurane
propofol
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2024.1332791/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2024.1332791/full

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