Osteochondral tissue engineering using a biphasic collagen/GAG scaffold containing rhFGF18 or BMP‐7 in an ovine model

Abstract Background The aim of this study was to investigate the effect of combining rhFGF18 or BMP‐7 with a biphasic collagen/GAG osteochondral scaffold (Chondromimetic) on the repair of osteochondral defects in sheep. Methods Osteochondral defects (5.8×6mm) were created in the medial femoral condy...

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Bibliographic Details
Main Authors: Alan Getgood, Frances Henson, Carrie Skelton, Roger Brooks, Hans Guehring, Lisa A Fortier, Neil Rushton
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Journal of Experimental Orthopaedics
Subjects:
Online Access:https://doi.org/10.1186/s40634-014-0013-x