Loss of GABARAPL1 confers ferroptosis resistance to cancer stem‐like cells in hepatocellular carcinoma

Loss of GABARAPL1 confers ferroptosis resistance to cancer stem‐like cells in hepatocellular carcinoma

Cancer stem‐like cells (CSLC) are considered a major contributor to the development and progression of hepatocellular carcinoma (HCC). Previous studies indicated that CSLC are characterized by resistance to ferroptosis, a type of lipid peroxidation‐dependent cell death. Here, we identified a set of...

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Bibliographic Details
Main Authors: Xiaojing Du, Zhuoran Qi, Jinzhi Xu, Mengzhou Guo, Xingxing Zhang, Zhijie Yu, Xin Cao, Jinglin Xia
Format: Article
Language:English
Published: Wiley 2022-10-01
Series:Molecular Oncology
Subjects:
cancer stem‐like cell
ferroptosis
GABARAPL1
hepatocellular carcinoma
sorafenib
Online Access:https://doi.org/10.1002/1878-0261.13305

Internet

https://doi.org/10.1002/1878-0261.13305

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