Nitrogen-Containing Bisphosphonates Downregulate Cathepsin K and Upregulate Annexin V in Osteoclasts Cultured In Vitro
Introduction. Bisphosphonates are widely used in the treatment of osteoporosis; however, they are associated with the serious adverse event of bisphosphonate‐related osteonecrosis of the jaw (BRONJ). Aim. The aim of this study is to assess the effects of nitrogen-containing bisphosphonates (N-PHs) o...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2023-01-01
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Series: | International Journal of Dentistry |
Online Access: | http://dx.doi.org/10.1155/2023/2960941 |