ECSIT Is a Critical Factor for Controlling Intestinal Homeostasis and Tumorigenesis through Regulating the Translation of YAP Protein

ECSIT Is a Critical Factor for Controlling Intestinal Homeostasis and Tumorigenesis through Regulating the Translation of YAP Protein

Abstract The intestinal epithelium is the fastest renewing tissue in mammals and its regenerative process must be tightly controlled to minimize the risk of dysfunction and tumorigenesis. The orderly expression and activation of Yes‐associated protein (YAP) are the key steps in driving intestinal re...

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Bibliographic Details
Main Authors: Yuying Jiang, Chunmei Ma, Yingchao Hu, Yongbing Yang, Chanyuan Ma, Chunyan Wu, Lu Liu, Shuang Wen, Paul N. Moynagh, Bingwei Wang, Shuo Yang
Format: Article
Language:English
Published: Wiley 2023-09-01
Series:Advanced Science
Subjects:
evolutionarily conserved signaling intermediate in Toll pathways
intestinal differentiation and tumorigenesis
YAP
Online Access:https://doi.org/10.1002/advs.202205180

Internet

https://doi.org/10.1002/advs.202205180

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